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Armin Kurtz Selected Research

Gap Junction alpha-5 Protein

4/2015Connexins, renin cell displacement and hypertension.
3/2015Inducible deletion of connexin 40 in adult mice causes hypertension and disrupts pressure control of renin secretion.
6/2011The connexin 40 A96S mutation causes renin-dependent hypertension.
10/2010Selective deletion of Connexin 40 in renin-producing cells impairs renal baroreceptor function and is associated with arterial hypertension.
8/2009Replacement of connexin 40 by connexin 45 causes ectopic localization of renin-producing cells in the kidney but maintains in vivo control of renin gene expression.

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Armin Kurtz Research Topics

Disease

16Hypoxia (Hypoxemia)
01/2022 - 05/2003
13Hypertension (High Blood Pressure)
01/2019 - 08/2002
6Hyperplasia
01/2018 - 05/2009
4Acute Kidney Injury (Acute Renal Failure)
11/2020 - 04/2007
4Ischemia
11/2011 - 05/2004
4Inflammation (Inflammations)
04/2007 - 01/2002
3Fibrosis (Cirrhosis)
01/2021 - 01/2004
3Renal Artery Obstruction (Renal Artery Stenosis)
05/2012 - 03/2003
3Sepsis (Septicemia)
01/2010 - 04/2002
3Shock
01/2010 - 04/2002
2Anemia
12/2015 - 05/2004
2Septic Shock (Toxic Shock Syndrome)
01/2010 - 04/2002
2Hypotension (Low Blood Pressure)
04/2007 - 10/2005
2Endotoxemia
02/2003 - 04/2002
1Ureteral Obstruction
10/2020
1Glomerulonephritis
01/2018
1Neoplasms (Cancer)
07/2017
1Hypertrophy
02/2013
1Reperfusion Injury
04/2007
1Hydronephrosis
07/2004
1Hemorrhage
05/2004
1Infarction (Infarctions)
05/2004
1Pathologic Constriction (Stenosis)
05/2004
1Renovascular Hypertension (Goldblatt Syndrome)
01/2004
1Proteinuria
01/2004
1Hepatocellular Carcinoma (Hepatoma)
11/2003
1Cardiovascular Diseases (Cardiovascular Disease)
11/2002
1Body Weight (Weight, Body)
08/2002
1Genetic Predisposition to Disease (Genetic Predisposition)
08/2002
1Deafness (Deaf Mutism)
06/2002

Drug/Important Bio-Agent (IBA)

19ReninIBA
01/2022 - 01/2004
12Transcription Factors (Transcription Factor)IBA
01/2022 - 05/2003
10Proteins (Proteins, Gene)FDA Link
01/2022 - 06/2002
6Oxygen (Dioxygen)IBA
01/2022 - 05/2004
6SaltsIBA
05/2012 - 06/2002
5Gap Junction alpha-5 ProteinIBA
04/2015 - 08/2009
4ErythropoietinFDA Link
01/2022 - 12/2015
4Angiotensin IIIBA
01/2019 - 10/2007
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2010 - 04/2002
4CytokinesIBA
01/2010 - 04/2002
3Protein Isoforms (Isoforms)IBA
01/2022 - 05/2003
3Deferoxamine (Desferal)FDA LinkGeneric
05/2004 - 05/2003
3Messenger RNA (mRNA)IBA
05/2004 - 02/2003
2CollagenIBA
01/2021 - 11/2003
2Carbon MonoxideIBA
10/2020 - 05/2004
2EnzymesIBA
11/2011 - 11/2003
2SodiumIBA
04/2007 - 01/2004
2cobaltous chloride (cobalt(II)chloride)IBA
05/2004 - 11/2003
2CobaltIBA
05/2004 - 05/2003
2AdrenomedullinIBA
05/2004 - 01/2002
2Interleukin-1beta (Interleukin 1 beta)IBA
02/2003 - 04/2002
2LipopolysaccharidesIBA
02/2003 - 04/2002
1Ligases (Synthetase)IBA
01/2022
1UbiquitinIBA
01/2022
1AdenineFDA LinkGeneric
01/2021
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2021
1Antihypertensive Agents (Antihypertensives)IBA
11/2020
1DiureticsIBA
11/2020
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
11/2020
1arginine methyl esterIBA
01/2019
1Chemokine ReceptorsIBA
01/2018
1ConnexinsIBA
04/2015
1Guanylate Cyclase (Guanylyl Cyclase)IBA
02/2013
1EnalaprilFDA LinkGeneric
02/2013
1AngiotensinsIBA
02/2013
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
02/2013
1Nitric Oxide Synthase (NO Synthase)IBA
02/2013
1NG-Nitroarginine Methyl Ester (L-NAME)IBA
02/2013
1Lactic Acid (Lactate)FDA LinkGeneric
11/2011
1DioxygenasesIBA
11/2010
1Small Interfering RNA (siRNA)IBA
01/2010
1NF-kappa B (NF-kB)IBA
01/2010
1Interleukin-6 (Interleukin 6)IBA
01/2010
1Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
05/2009
1Contrast MediaIBA
05/2009
1Vascular Endothelial Growth Factor CIBA
05/2009
1Cisplatin (Platino)FDA LinkGeneric
05/2009
1ProstaglandinsIBA
10/2007
1Phenylephrine (Neo-Synephrine)FDA LinkGeneric
10/2005
1Triose-Phosphate Isomerase (Triosephosphate Isomerase)IBA
05/2004
1Aryl Hydrocarbon Receptor Nuclear TranslocatorIBA
05/2004
1Urea (Carbamide)FDA LinkGeneric
01/2004
1Celecoxib (Celebrex)FDA Link
01/2004
1CreatinineIBA
01/2004
1Chelating AgentsIBA
11/2003
1IronIBA
11/2003
1ProcollagenIBA
11/2003
1Mixed Function Oxygenases (Monooxygenases)IBA
11/2003
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
05/2003
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
03/2003
1Furosemide (Lasix)FDA LinkGeneric
03/2003
1Norepinephrine (Noradrenaline)FDA LinkGeneric
02/2003
1Nitric Oxide (Nitrogen Monoxide)FDA Link
02/2003
1Nitric Oxide DonorsIBA
02/2003
1rofecoxib (Vioxx)FDA Link
08/2002

Therapy/Procedure

2Sodium-Restricted Diet (Diet, Sodium Restricted)
02/2013 - 03/2003
2Ligation
01/2010 - 07/2004
1Punctures
01/2010
1Subcutaneous Injections
10/2005
1Surgical Instruments (Clip)
01/2004